It's got some of the best voice acting ever and the fact that Simon Templeman continues to use the Kain voice makes me so happy at times. See also: Loghain from Dragon Age.
I mean it's not without it's faults - Blood Omen 2 is basically the black sheep of the series as it's... a bit disconnected story wise from the rest of the games and the combat system is not the greatest.
I would happily roleplay characters from this series again if I could find the time. It's been years since I played from it... or even replayed the games for that matter.